About the MBCGA Advocate Research Committee
The MBCGA Advocate Research Committee focuses on matters relating to research specific to or related to male breast cancer.
The committee will be involved with:
- Recommending which research proposals, the MBCGA will support through funding, promoting, or other means.
- Meeting with researchers that approach the MBCGA for input or assistance.
- Meet with Pharmaceutical Trial representatives as needed to provide the male breast cancer patient input for new trials.
- Recommending and assisting with virtual meetings that present male breast cancer research.
- Reviewing MBCGA materials (e.g., handouts, website, etc.) to be sure that they are consistent with the latest evidence.
- Mentoring new male cancer advocates interested in learning more about research advocacy.
Committee Membership:
- Ideally, members will have participated in Project LEAD, the Scientist-Survivor Program of the American Association for Cancer Research, or other cancer research training programs.
- Members who have not attended a research training program are welcomed to participate but are strongly encouraged to apply for one. (The more experienced advocates on the committee can help).
- Members are committed to using an evidence-based approach to their work within the committee.
Current Clinical Trials focused on Male Breast Cancer
ETHAN Trial: A phase II study comparing different Endocrine Therapies for male breast cancer
Exploring Treatment Patterns and Outcomes in Men with Breast Cancer, Vanderbilt University
Interested in learning more about breast cancer research and becoming engaged with our research committee? We want you! One of the goals of our research committee is to encourage and nurture more men to become breast cancer research advocates through training programs like the National Breast Cancer Coalition’s Project LEAD, Komen’s Advocates in Science Program, the Alamo Breast Cancer Foundation Patient Advocate Program, and the American Association for Cancer Research’s Scientist-Survivor Program.
Committee lead members Bob Ritter, Rod Ritchie and Michael Singer have been involved in these activities and would be happy to share their experiences with you. Reach out by email to join our research committee.
EMAIL: support@mbcga.org
More trials from ClinicalTrials.com
Notable Publications on Male Breast Cancer (Open-Access)
General Reviews
Male breast cancer in the United States: Treatment patterns and prognostic factors in the 21st century
Yadav, S., Karam, D., Bin Riaz, I., Xie, H., Durani, U., Duma, N., Giridhar, K.V., Hieken, T.J., Boughey, J.C., Mutter, R.W., Hawse, J.R., Jimenez, R.E., Couch, F.J., Leon-Ferre, R.A. and Ruddy, K.J. (2020), Male breast cancer in the United States: Treatment patterns and prognostic factors in the 21st century. Cancer, 126: 26-36. https://doi.org/10.1002/cncr.32472
Male Breast Cancer: An Updated Review of Epidemiology, Clinicopathology, and Treatment
Zheng, Guoliang, Leone, Jose Pablo, Male Breast Cancer: An Updated Review of Epidemiology, Clinicopathology, and Treatment, Journal of Oncology, 2022, 1734049, 11 pages, 2022. https://doi.org/10.1155/2022/1734049
Current Perspectives on Non-Metastatic Male Breast Cancer: Genetics, Biology, and Treatment Advances: A Systematic Review
Melan, K.; Loap, P.; Kirova, Y. Current Perspectives on Non-Metastatic Male Breast Cancer: Genetics, Biology, and Treatment Advances: A Systematic Review. Cancers 2025, 17, 3270. https://doi.org/10.3390/cancers17193270
Screening and Risk Factors
ACR Appropriateness Criteria® Male Breast Cancer Screening
ACR Appropriateness Criteria® Male Breast Cancer Screening, Expert Panel on Breast Imaging et al., Journal of the American College of Radiology, Volume 22, Issue 11, S578 – S585
Risk factors for male breast cancer
Fentiman IS. Risk factors for male breast cancer. Am J Transl Res. 2023 Dec 15;15(12):6918-6925. PMID: 38186995; PMCID: PMC10767513.
Imaging
Male Breast Cancer: Imaging Considerations for Diagnosis and Surveillance
THOMAS, M., AL KASHROOM, H., REDDY, S., ZACCARINI, D., WILLER, K.. Male Breast Cancer: Imaging Considerations for Diagnosis and Surveillance. Journal of Clinical Medicine Research, North America, 16, May. 2024.
Male breast MRI: a review of different pathological conditions
åBarillari, M., Zanutto, P., Pellini, F. et al. Male breast MRI: a review of different pathological conditions. Radiol med 130, 1752–1766 (2025). https://doi.org/10.1007/s11547-025-02084-x
Treatment Guidelines
Male Breast Cancer Treatment (PDQ®). Health Professional Version. National Library of Medicine. (2025)
Management of Male Breast Cancer: ASCO Guidelines
Michael J. Hassett, Mark R. Somerfield, Elisha R. Baker, Fatima Cardoso, Kari J. Kansal, Dylan C. Kwait, Jennifer K. Plichta, Charité Ricker, Anna Roshal, Kathryn J. Ruddy, Joshua D. Safer, Catherine Van Poznak, Rachel L. Yung, Sharon H. Giordano Journal of Clinical Oncology 2020 38:16, 1849-1863
Efficacy of neoadjuvant chemotherapy in male breast cancer compared with female breast cancer
Leone JP, Hassett MJ, Leone J, Tolaney SM, Vallejo CT, Leone BA, Winer EP, Lin NU. Efficacy of neoadjuvant chemotherapy in male breast cancer compared with female breast cancer. Cancer. 2022 Nov 1;128(21):3796-3803. doi: 10.1002/cncr.34448. Epub 2022 Sep 7. PMID: 36069365; PMCID: PMC9826058
Biology
Genomic profiling and comparative analysis of male versus female metastatic breast cancer across subtypes
Kadamkulam Syriac, A., Nandu, N.S., Clark, A. et al. Genomic profiling and comparative analysis of male versus female metastatic breast cancer across subtypes. Breast Cancer Res 26, 118 (2024). https://doi.org/10.1186/s13058-024-01872-z
Survival
Mortality Risks Over 20 Years in Men With Stage I to III Hormone Receptor-Positive Breast Cancer
Leone J, Hassett MJ, Freedman RA, Tolaney SM, Graham N, Tayob N, Vallejo CT, Winer EP, Lin NU, Leone JP. Mortality Risks Over 20 Years in Men With Stage I to III Hormone Receptor-Positive Breast Cancer. JAMA Oncol. 2024 Apr 1;10(4):508-515. doi: 10.1001/jamaoncol.2023.7194. PMID: 38421673; PMCID: PMC10905378.
Survival in male breast cancer over the past 3 decades
José P Leone, Rachel A Freedman, Julieta Leone, Sara M Tolaney, Carlos T Vallejo, Bernardo A Leone, Eric P Winer, Nancy U Lin, Michael J Hassett, Survival in male breast cancer over the past 3 decades, JNCI: Journal of the National Cancer Institute, Volume 115, Issue 4, April 2023, Pages 421–428, https://doi.org/10.1093/jnci/djac241
Quality of Life
Quality of Life in Male Breast Cancer: Prospective Study of the International Male Breast Cancer Program (EORTC10085/TBCRC029/BIG2-07/NABCG)
Carolien P Schröder, Elise van Leeuwen-Stok, Fatima Cardoso, Barbro Linderholm, Coralie Poncet, Antonio C Wolff, Vesna Bjelic-Radisic, Gustavo Werutsky, Miguel H Abreu, Ivana Bozovic-Spasojevic, Irma den Hoed, Aafke H Honkoop, Maartje Los, Jose P Leone, Nicola S Russell, Tineke J Smilde, Annette W G van der Velden, Catherine Van Poznak, Marije M Vleugel, Rachel L Yung, Corneel Coens, Sharon H Giordano, Kathryn J Ruddy, Quality of Life in Male Breast Cancer: Prospective Study of the International Male Breast Cancer Program (EORTC10085/TBCRC029/BIG2-07/NABCG), The Oncologist, Volume 28, Issue 10, October 2023, Pages e877–e883, https://doi.org/10.1093/oncolo/oyad152